MOBILE GENOMES
'We investigate the patterns and mechanisms of genomic variation in disease'
My interest in bioinformatics started while working in my BSc thesis about biomedical image analysis, where I used machine learning to identify macular edema regions in OCT scans. Since then, I have been looking for ways to apply my computer science's knowledge in this field. I am currently stuying tumour-specific changes in the 3D organisation of non-small cell lung cancer samples, which is the main focus of my PhD thesis. Previously, I have also worked in the detection of genetic variants responsible for transmissibility on a project that studies the genetic mechanisms of transmissible cancer in cockles.
Education, Grants and Awards
2020-present: PhD in Molecular Medicine at University of Santiago de Compostela, Spain.
2018-2020: MSc. in Bioinformatics for Health Sciences at University of A Coruña, Spain.
2018-2019: Research Collaboration Grant in Computer Science Department at University of A Coruña, Spain.
2014-2018: BSc. in Computer Engineering at University of A Coruña, Spain:
Publications
Characterization of Human Herpesvirus 8 genomic integration and amplification events in a primary effusion lymphoma cell line. Álvarez, E. G.; Otero, P.; Rodríguez-Martín, B.; Pequeño-Valtierra, A.; Otero, I.; ... & García-Souto, D. Frontiers in Virology 3, (2023). https://doi.org/10.3389/fviro.2023.1253416
Somatic evolution of marine transmissible leukemias in the common cockle, Cerastoderma edule. Bruzos, A.L.; Santamarina, M.; García-Souto, D. et al. Nat Cancer 4, 1575–1591 (2023). https://doi.org/10.1038/s43018-023-00641-9
Aberrant integration of Hepatitis B virus DNA promotes major restructuring of human hepatocellular carcinoma genome architecture. Álvarez, E.G.; Demeulemeester, J.; Otero, P. et al. Nat Commun 12, 6910 (2021). https://doi.org/10.1038/s41467-021-26805-8
Prediction of Antimalarial Drug-Decorated Nanoparticle Delivery Systems with Random Forest Models. Urista, D. V.; Carrué, D. B.; Otero, I.; Arrasate, S.; Quevedo-Tumailli, V. F.; Gestal, M.; ... & Munteanu, C. R. Biology 9, no. 8 (2020): 198. https://doi.org/10.3390/biology9080198
Automatic Tool for the Detection, Characterization and Intuitive Visualization of Macular Edema Regions in OCT Images. Otero, I.; Vidal, P.L.; Moura, J. et al. Proceedings of The 2nd XoveTIC Conference (XoveTIC 2019). https://doi.org/10.3390/proceedings2019021036
Computerized tool for identification and enhanced visualization of Macular Edema regions using OCT scans. Otero, I.; Vidal, P.L.; Moura, J. et al. Proceedings of the European Symposium on Artificial Neural Networks, Computational Intelligence and Machine Learning, Bruges, Belgium (pp. 24-26). https://www.elen.ucl.ac.be/Proceedings/esann/esannpdf/es2019-21.pdf
