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MOBILE GENOMES

'We investigate the patterns and mechanisms of genomic variation in disease'

Paula Otero, PhD student

paulaotero.sanchez@.usc.es

Some years ago, I got a BSc in Biomedical Science at the University of Lleida. At that point I started to be interested in genetics and that's why, back in Galicia, I completed a MSc in Genomics and Genetics. Now, I would like to grow as a scientist and continue my studies focusing on the analysis of the genetic basis of human diseases. In my spare time, I love reading, F1 and eating popcorn. Also, I swim without floats.

Education, Grants and Awards

May-Jul 2022 Research Stay: Cristofari Lab, Institute for Research on Cancer and Aging, Nice (IRCAN). Funding: Ministry of Education, Spanish Government.

2019 Extraordinary award in Biomedical Science, University of Lleida.

2019/2023 Predoctoral fellowship, FPU, Ministry of Universities, Spanish Government.

2018/2019 MSc in Genomics and Genetics University of Santiago de Compostela, Spain.

2018/2019 MEFP collaboration scholarship. Zoology, Genetics and Physical Antropology department. Genetics area.

2018 Impuls Program Award for the best student in Biomedical Science - Faculty of Medicine, University of Lleida.

2018 Research Training Grant – Center for Research in Molecular Medicine and Chronic Diseases (CIMUS), University of Santiago de Compostela, Spain.

2014-2018 BSc in Biomedical Science. University of Lleida, Spain.

Projects

Epilepsy project

Publications and Conferences

  1. Otero-Sánchez, P., Rodríguez-Martín, B., García-Souto, D., Tubio, JMC. Identification of genetic variants in a human genome by means of whole-exome sequencing analysis. 2018. ASCB|EMBO Meeting, San Diego, CA. (Poster)
  2. Otero-Sánchez, P., G. Álvarez,E., Rodríguez-Fontenla, M.C., Temes, J., Tubio, JMC. Identification of genomic rearrangements in human diseases using single-molecule sequencing technologies. 2019. II annual CiMUS Workshop. Santiago de Compostela. (Poster)
  3. Otero-Sánchez, P., Single-molecule sequencing technologies as a promising alternative for the identification of genomic rearrangements in human diseases. 2019. IBCG2019. A Coruña. (Oral presentation)
  4. Otero, P., Temes, J., García-Souto, D., Tubio, JMC. SVi: a new tool to easily and fast benchmark, process, integrate and represent genomic structural variation. 2020. III annual CiMUS Workshop. Santiago de Compostela. (Poster)
  5. Otero, P., Álvarez, E.G., García-Souto, D., Temes, J., Tubio, JMC. Analysis of HPV integration patterns in a cervical cancer cell line using single-molecule sequencing technologies. 2021. VIII Encontro da Mocidade Investigadora. Santiago de Compostela (Oral presentation)
  6. Otero, P., Álvarez, E.G., García-Souto, D., Temes, J., Tubio, JMC. New insights into HPV integration in cancer revealed by single-molecule sequencing technologies. 2021. IBCG. A Coruña. (Poster)
  7. Coedo, C., Abal, R., Pequeño, A., Tubio, JMC, Otero, P.# Identification of a germiline genetic variant related to familiar multiple endocrine neoplasias. 2021. IV CiMUS Workshop. Santiago de Compostela. (Poster) (#Corresponding author)
  8. Álvarez, E.G., Demeulemeester, J.#, Otero, P.#, Jolly, C.#, García-Souto, D.#, et al. Aberrant integration of hepatitis B virus DNA promotes major restructuring of human hepatocellular carcinoma genome architecture. 2021, Nature Communications, (12) 6910. (#equal contribution)
  9. Otero, P., Álvarez, E.G., Pérez-del-Pulgar, S., Tubio, JMC. HBV-mediated genomic rearrangements and their impact on the origins of hepatocellular carcinoma. 2022. Cancer Genomics EACR. Oxford, UK. (Poster)

Dissemination activities

CiMUS Podcast

Ciencia e Tal