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MOBILE GENOMES & DISEASE

'We investigate the impact of mobile DNA on disease, and the genetic mechanisms that make cancers transmissible'

Eva G. Alvarez, PhD student | Cancer Virome

eva.gaal93@gmail.com

I have always been interested in genomics, even more since I had the opportunity of working at a wet-lab during the two last years of my degree in Biology at UDC (Universidade da Coruña). After that, I got a fellowship that allowed me to study a MSc in Bioinformatics at UAB (Universitat Autònoma de Barcelona) and I love working in this field.

As a member of the Mobile Genomes and Disease team, I am studying the mobile DNA in cancer genomes. In particular, my PhD thesis is focused on studying viral integration in these genomes, even though I also have a look to other types of mobile DNA, specially retrotransposons.

I am working with some other Mobile Genomes’ researchers in the project called “Cancer Virome” . Our aim is to characterize the relationship between viruses and cancer. Therefore, we are focused on known cancer viruses as well as on novel interactions between cancer cells and viruses.

Grants and awards

Publications

Pan-cancer analysis of whole genomes reveals driver rearrangements promoted by LINE-1 retrotransposition in human tumours.
Bernardo Rodríguez-Martín, Eva G. Alvarez, Adrian Baez-Ortega et al.
bioRxiv posted August 24, 2017
doi: https://doi.org/10.1101/179705

Germline determinants of the somatic mutation landscape in 2,642 cancer genomes.
Sebastian M. Waszak, Grace Tiao, Bin Zhu et al. (Includes Eva G. Alvarez)
bioRxiv posted November 1, 2017
doi: https://doi.org/10.1101/208330

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