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MOBILE GENOMES & DISEASE

'We investigate the impact of mobile DNA on disease, and the genetic mechanisms that make cancers transmissible'

Daniel Garcia Souto, PhD in Biology | Cytogenetist

danielgarciasouto@gmail.com

Recent PhD in bivalve cytogenetics at UVIGO (2017), my line of research has focused on karyological evolution, non-coding satellite DNA and epigenetics in marine molluscs by means of techniques such as fluorescent in situ hybridization, phylogenetic analysis and epigenetic studies of methylation by immunodetection, AFLPs, ELISA and post-bisulfite transformation sequencing. As a PhD student I performed research stays at the Ruđer Bošković Institute of Zagreb (Croatia, 2015) and at the International University of Miami (USA, 2016). I love kayaking and cycling.


Selected publications (last 5 years)


Are Pericentric Inversions Reorganizing Wedge Shell Genomes?.
D. García-Souto; C. Pérez-García; JJ Pasantes.
Genes (Basel). 7 - 8 (12), pp. E370. 2017.

Detection of invasive and cryptic species in marine mussels (Bivalvia, Mytilidae): A chromosomal perspective.
D. García-Souto; A. Sumner-Hempel; S. Fervenza; C. Pérez-García; A. Torreiro; R. González-Romero; J.M. Eirín-López; P. Morán; J.J. Pasantes.
Journal for Nature Conservation. 39, pp. 58 - 67. 2017.

Effects of Florida Red Tides on histone variant expression and DNA methylation in the Eastern oyster Crassostrea virginica.
R. Gonzalez-Romero; V. Suarez-Ulloa; J. Rodriguez-Casariego; D. Garcia-Souto; G. Diaz; A. Smith; J.J. Pasantes; G. Rand; J.M. Eirin-Lopez.
Aquatic Toxicology. 186, pp. 196 - 204. 2017.

Epigenetic DNA methylation mediating Octopus vulgaris early development: Effect of essential fatty acids enriched diet.
P. García-Fernández; D. García-Souto; E. Almansa; P. Morán; C. Gestal.
Frontiers in Physiology. 8 - 16, pp. 292. 2017.

Karyotype differentiation in tellin shells (Bivalvia: Tellinidae).
D. García-Souto; G. Ríos; J.J. Pasantes.
BMC Genetics. 18 - 1, pp. 66. 2017.

Methylation profile of a satellite DNA constituting the intercalary G+C-rich heterochromatin of the cut trough shell Spisula subtruncata (Bivalvia, Mactridae).
D. García-Souto; B. Mravinac; E. Šatović; M. Plohl; P. Morán; J.J. Pasantes.
Scientific Reports. 7(1), pp. 6930. 2017.

Resolving the Taxonomic Status of Chamelea gallina and C. striatula (Veneridae, Bivalvia): A Combined Molecular Cytogenetic and Phylogenetic Approach.
D. García-Souto; V. Qarkaxhija; J.J. Pasantes.
BioMed Research International. 2017, pp. 7638790. 2017.

Molecular cytogenetics in digenean parasites: Linked and unlinked Major and 5S rDNAs, B chromosomes and karyotype diversification.
D. García-Souto; J.J. Pasantes.
Cytogenetic and Genome Research. 147 - (2-3) 1, pp. 195 - 207. 2016.

Molecular cytogenetics in trough shells (Mactridae, Bivalvia): Divergent GC-rich heterochromatin content.
D. García-Souto; C. Pérez-García; J. Kendall; J.J. Pasantes.
Genes (Basel). 7 - 8, pp. 47. 2016.

Divergent evolutionary behavior of H3 histone gene and rDNA clusters in venerid clams.
D. García-Souto; C. Pérez-García; P. Morán; J.J. Pasantes.
Molecular Cytogenetics. 8 - 1, pp. 40. 2015.

Molecular cytogenetic analysis of the European hake Merluccius merluccius (Merlucciidae, Gadiformes): U1 and U2 snRNA gene clusters map to the same location.
D. García-Souto; T. Troncoso; M. Pérez; J.J. Pasantes.
PLoS ONE. 10 - 12, pp. e0146150. 2015.

Zoledronic acid as an antimetastatic agent for different human tumor cell lines.
L. Muinelo-Romay; D. García; L. Alonso-Alconada; M. Vieito; M. Carmona; N. Martínez; S. Aguín; M. Abal; R. López-López.
Anticancer research. 33 - 12, pp. 5295 - 5300. 2013.