'We investigate the impact of mobile DNA on disease, and the genetic mechanisms that make cancers transmissible'

Alicia L. Bruzos, PhD student | Cancer Transmissibility


While being a student the eagerness of researching was awakened in me and I’ve got the opportunity to collaborate in some research projects that gave me a solid platform to decide to do a PhD. I am currently studying the genetic mechanisms of transmissible cancers using the disseminated neoplasia of cockles as a model. In my spare time, I have a strong desire travel and explore the world and when possible I like to do it with my friends, family and pets. I consider myself a wanderlust soul.



One goal of my thesis is to validate genetic variants by gene-editing approaches. Nowadays, I am at the Pacific Northwest Research Institute (Seattle, USA) for a three-month research stay learning how to use CRISPR-Cas9 system to modify bivalves genome.



Pan-cancer analysis of whole genomes reveals driver rearrangements promoted by LINE-1 retrotransposition in human tumours. Bernardo Rodríguez-Martín, Eva G. Alvarez, Adrian Baez-Ortega et al. (Includes Alicia L. Bruzos)
bioRxiv posted August 24, 2017
doi: https://doi.org/10.1101/179705

Germline determinants of the somatic mutation landscape in 2,642 cancer genomes. Sebastian M. Waszak, Grace Tiao, Bin Zhu et al. (Includes Alicia L. Bruzos)
bioRxiv posted November 1, 2017
doi: https://doi.org/10.1101/208330

Book chapters:

Primeros pasos para decodificar el genoma de berberecho, Cerastoderma edule (Linnaeus, 1758). Alicia L. Bruzos, Seila Díaz, Daniel García-Souto, Jorge Zamora, Jose Tubío (2017). In: Rey-Méndez M., Fernández Casal J, Guerra A, Lastres M.A., Padín X.A., Lodeiros C. (Eds.). Foro dos Recursos Mariños e da Acuicultura das Rías Galegas. 20: 227-237. ISBN: 978-84-09-01474-3; depósito legal: C 2014-2016

Genoma de referencia de berberecho: estimación de su tamaño. Alicia L. Bruzos, Seila Díaz, Daniel García-Souto, Jorge Zamora, Jose Tubío (2017). In: Jóvenes Investigadores 2017 (pp. 47-51). Salamanca, Spain. ISBN: 978-84-945079-9-1; depósito legal: S.469-2017




Twitter: @BruzosAliciaL

“The pursuit of PhD is an enduring daring adventure.” ― Lailah Gifty Akita